Idebenone does not inhibit disability progression in primary progressive MS
نویسندگان
چکیده
منابع مشابه
Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS
BACKGROUND Multiple Sclerosis is more common in women than men and females have more relapses than men. In a large international cohort we have evaluated the effect of gender on disability accumulation and disease progression to determine if male MS patients have a worse clinical outcome than females. METHODS Using the MSBase Registry, data from 15,826 MS patients from 25 countries was analys...
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Multiple sclerosis is a CNS autoimmune disease configured by demyelination, inflammation, and degeneration of axons. This disease inflict great harms to patients. The most common problem is inability to control musculoskeletal system and decrease in mobility. These consequences could vary from patients to patients. About 10-15% of all MS patients develop primary progressive MS (PPMS). Despite t...
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OBJECTIVE To investigate whether the structural connectivity of the brain's rich-club organization is altered in patients with primary progressive MS and whether such changes to this fundamental network feature are associated with disability measures. METHODS We recruited 37 patients with primary progressive MS and 21 healthy controls for an observational cohort study. Structural connectomes ...
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ژورنال
عنوان ژورنال: Multiple Sclerosis and Related Disorders
سال: 2020
ISSN: 2211-0348
DOI: 10.1016/j.msard.2020.102434